diff --git a/src/util/00-mesa-defaults.conf b/src/util/00-mesa-defaults.conf
index f8e76f92e38..f1bcae4e702 100644
--- a/src/util/00-mesa-defaults.conf
+++ b/src/util/00-mesa-defaults.conf
@@ -1300,6 +1300,10 @@ TODO: document the other workarounds.
         <engine engine_name_match="Source2">
             <option name="anv_enable_buffer_comp" value="true" />
         </engine>
+        <!-- Many DX12 games get a speedup by enabling buffer compression. -->
+        <engine engine_name_match="vkd3d">
+            <option name="anv_enable_buffer_comp" value="true" />
+        </engine>
         <!--
         Disable 16-bit feature on zink and angle so that GLES mediump doesn't
         lower to our inefficent 16-bit shader support.  No need to do so for